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Dementia Fast Facts

Dementia is a general description for disorders that cause problems with memory, cognition, and behavior. These symptoms may come from a variety of causes. An estimated 46 million people worldwide suffer from various forms of dementia. That number is predicted to rise to more than 131 million by 2050 Those who care for people with dementia are at risk of developing physical, mental, and emotional problems of their own, not to mention being faced with sometimes severe financial strain.

Although it often affects the elderly, dementia can affect those under the age of 50, and dementia is not an inevitable part of the aging process. Women are disproportionately affected by dementia, both because they are more likely to develop it and because they are more likely than men to be caregivers for loved ones with dementia.

The estimated economic cost of caring for those with dementia is $818 billion annually.

What is Dementia?

Dementia is a general term for changes in brain function that results in problems with memory, thought processes, and behavior. The term is used to describe a cluster of symptoms, and those symptoms may be caused by several different diseases or disorders, as well as injuries or other neurological events.

Symptoms of Dementia

Symptoms of dementia differ from case to case, but in order to be clinically diagnosed as dementia, symptoms must include significant impairment in at least two of these core brain functions:

  • Memory. Sufferers often struggle with short-term memory loss, and as the disorder progresses, memory loss becomes more severe. Dementia patients very often forget where they put things.
  • Language. Sufferers often have trouble communicating because they struggle to find the right words to express themselves. Communication problems also become more severe as the disorder progresses.
  • Attention. Sufferers may have trouble concentrating or maintaining focused attention on a task or a subject. They may have trouble planning or organizing their thoughts.
  • Reasoning. Sufferers are often unable to complete complex tasks or solve problems, and they may become confused or disoriented.
  • Visual perception. Sufferers have trouble processing visual or spatial information, and they may become disoriented easily. This disorientation can lead to getting lost or not understanding where they are.

Dementia also often causes changes in behavior, including:

  • Depression or anxiety
  • Hallucinations, delusions or paranoia
  • Frustration or extreme agitation
  • Inappropriate or irrational behavior

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

What Causes Dementia?

Dementia symptoms stem from a wide range of causes. Some of the causes are distinct brain diseases, and others are neurological events that result in changes in brain function. The most common causes of dementia include:

  • Alzheimer’s disease. Alzheimer’s is the most common cause of dementia, accounting for 60-80% of all cases. The disease results from abnormal protein clusters in the brain that interfere with and damage healthy neurons.
  • Vascular dementia. The second-most common cause of dementia happens when blood flow to the brain is disrupted, often because of a stroke, injury, or other neurological events. This kind of dementia more often causes problems with thought processes than with memory loss.
  • Lewy body dementia. This form of dementia is also linked to abnormal protein clumping in the brain, and it is associated with Parkinson’s disease as well as Alzheimer’s. Common symptoms include hallucinations and physical tremors.
  • Frontotemporal dementia. This type of dementia is associated with the degeneration of neurons in the brain’s frontal and temporal lobes, the parts of the brain responsible for personality and language.
  • Traumatic brain injury (TBI). Repetitive injuries to the brain over time can eventually cause symptoms of dementia. This type of dementia often affects athletes who experience traumas to the head frequently.

Other causes of dementia include brain tumors, nutritional deficiencies, Creutzfeldt-Jakob disease, Parkinson’s disease, amyotrophic lateral sclerosis, thyroid problems, infections, and medication side effects.

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

Is Dementia Hereditary?

Because there are so many different causes of dementia, it is important to understand the details of your family history of dementia to know if there is a risk of inheriting the problem. Some causes of dementia show a strong link to family history, but most do not.

  • The most common cause of dementia, Alzheimer’s disease, may have a genetic component, but a family history of the disease does not necessarily increase risk. In general, heritability is most likely when a parent or grandparent developed the disease at a relatively early age.
  • Vascular dementia is not heritable on its own, but the underlying cause of dementia is often a condition such as heart disease or diabetes which may have a family-history connection.
  • Frontotemporal dementia (FTD) does seem to be heritable. About 40% of people diagnosed with FTD have a relative who has experienced some form of dementia (although not necessarily FTD).

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

How is Dementia Detected?

Although many causes of dementia are progressive and incurable, early detection of symptoms can allow you to get the treatment that can improve your quality of life over the course of the disease. Some causes of dementia are treatable and reversible, and early diagnosis of these forms of dementia is crucial in getting effective treatment.

The early indications of dementia include:

  • Memory loss. Minor memory problems are a natural part of the aging process, but dementia-related memory loss typically includes forgetting names or dates, needing to be reminded of the same things over and over, and loss of memories that don’t come back.
  • Problem-solving difficulties. These difficulties include having trouble doing tasks that you used to have no problem with, such as following a recipe or paying bills on time. Problems with attention or concentration are also a warning sign.
  • Disorientation. Dementia sufferers often have trouble remembering where they are or what the day or date is. They might get confused about the passage of time or have difficulty understanding spatial relationships.
  • Visual perception. Dementia often manifests in difficulties with color or depth perception, or other visual problems. These problems might show up while the sufferer is trying to read or drive.
  • Language problems. Difficulty finding the correct words for a situation or participating in a conversation is a common early warning sign of dementia.
  • Losing things. Dementia sufferers often misplace common objects such as keys, glasses, and wallets.
  • Poor judgment. Dementia sufferers often make bad decisions about finances, social situations, grooming, or hygiene.
  • Social struggles. Dementia sufferers also may begin to avoid social situations because of their difficulties in navigating them.
  • Personality changes. Uncharacteristic, unexplained anxiety, frustration, confusion, or paranoia are common early signs of dementia.

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

How is Dementia Diagnosed?

To pinpoint the cause of dementia symptoms, doctors look for a pattern of symptoms, risk factors, and family history. The diagnostic process typically includes physical examinations, tests, a review of medical and family history, and, often, information gathered from caregivers or loved ones.

Diagnostic steps may include:

  • A physical exam. This exam will be aimed at ruling out specific physical conditions that could be causing the symptoms.
  • Cognitive tests. These tests are aimed at measuring the patient’s ability to think clearly, and they target cognitive functions such as memory, reasoning, language, attention, and orientation.
  • Neurological tests. These tests measure the function of the patient’s nervous system. They evaluate functions such as balance, reflexes, memory, visual perception, and language.
  • Brain scans. These tests–such as MRIs, CTs, and PET scans– look for signs of bleeding in the brain, stroke, tumors, or protein deposits characteristic of Alzheimer’s.
  • Blood and laboratory tests. These tests will look at the patient’s blood chemistry for issues such as thyroid function, vitamin B-12 deficiency, or inflammation which may be causing the symptoms.
  • Psychological assessments. These assessments may take the form of questionnaires or talk sessions with a mental health professional to look for signs of depression or other mental issues that may be linked to the symptoms.

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

How is Dementia Treated?

Progressive forms of dementia such as those associated with Alzheimer’s, Parkinson’s, Lewy body dementia, and frontotemporal dementia are not curable, and no treatments have yet proven effective at slowing the progression of the disorder. Treatments are usually aimed at lessening the severity of the symptoms and improving the quality of life as the disease progresses.

Medication

Several different kinds of medication may be used to treat symptoms of dementia. The medications prescribed will depend on the cause of the symptoms, the specific symptoms being experienced, and their severity.

  • Cholinesterase inhibitors. These medications help to increase the level of a chemical called acetylcholine in the brain. Acetylcholine aids in the transmission of neurological signals in the brain and its absence can cause problems with memory and judgment. Cholinesterase inhibitors–which include donepezil, rivastigmine, and galantamine–are used most often to treat dementia in Alzheimer’s patients, but they are also sometimes prescribed for Lewy body dementia, vascular dementia, and Parkinson’s-related dementia.
  • Memantine. This medication works by limiting the level of a chemical called glutamate in the brain. Glutamate is a naturally occurring chemical that helps transmit neurological signals, but in this case, it’s thought that an excess of glutamate may cause damaging overstimulation of nerve cells. Memantine may help to improve memory and thought processes in dementia sufferers.
  • Antidepressants, antipsychotics, and other medications. Other medications are sometimes used to treat symptoms of dementia such as depression, hallucinations, or sleep disruptions.

Non-Drug Therapies

Non-drug therapies for treating dementia typically focus on making the sufferer’s environment as safe, comforting, and supportive as possible. Occupational therapy can be used to learn how to cope with the symptoms and progression of dementia, and modifications to the environment, such as increasing organization and decreasing distractions, can help the sufferer to stay safe and calm.

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

How Does Dementia Progress?

The most common types of dementia–including that caused by Alzheimer’s, Lewy body dementia, vascular dementia, and frontotemporal dementia–all get worse over time as the damage to the sufferer’s brain increases. Different types of dementia progress at different rates, with Alzheimer’s dementia, usually being one of the slowest types.

  • In Alzheimer’s, dementia typically progresses from mild memory and language problems, through increasingly severe states of confusion, to eventual extreme problems such as the inability to swallow, loss of speech, and incontinence.
  • Vascular dementia, depending on the cause, may progress quickly or slowly, and in late stages, it often closely resembles Alzheimer’s.
  • Lewy body dementia often causes hallucinations and movement problems in its early stages, but in its later stages, it also often resembles Alzheimer’s.
  • Early stages of frontotemporal dementia are sometimes characterized by behavior changes, personality changes, and language problems. As with other types of dementia, later stages tend to resemble those of Alzheimer’s.

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

How is Dementia Prevented?

Researchers have yet to discover a surefire way to know who will develop dementia, and there is no known way to prevent the onset of the disorder. Some research has suggested, however, that taking steps to boost your brain health throughout your life may help your body to hold off some forms of dementia. To have the best chance of keeping your brain healthy, follow these best practices:

  • Get as much mental exercise as possible. It’s possible that reading, doing puzzles, playing games, and engaging in activities that keep your mind active can help to delay the onset of dementia or decrease the severity of symptoms. Social activity likely helps, as well.
  • Get physical exercise, too. Physical activity keeps your body strong, and a strong body is more able to support good brain health.
  • Don’t smoke. Smoking, especially late in life, has been linked in some studies to an increased risk of developing dementia.
  • Pay attention to your heart health.  Disorders such as diabetes, high cholesterol, and high blood pressure are hard on your body’s cardiovascular system, and poor cardiovascular health can lead to neurological problems such as dementia. Treating these problems may lower your risk of developing dementia.
  • Focus on good nutrition. A diet that includes enough fruits, vegetables, whole grains, omega-3 fatty acids, and vitamin D may also help prevent dementia.
  • Get plenty of sleep. Poor sleep habits and sleep apnea have been implicated in the development of many long-term health problems, including dementia.

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

Dementia Caregiver Tips

Caring for someone with dementia is one of the most difficult responsibilities that any caregiver can face. Most caregivers are family members or loved ones, and they are unprepared and untrained for the extremely difficult job of keeping the sufferer safe and as comfortable as possible as the disease progresses. If you’re responsible for taking care of a dementia sufferer, keep these tips in mind:

  • Learn as much as possible about the specific type of dementia so that you understand what you’re facing now and what you’re likely to face in the future as the disorder progresses.
  • Be as involved as possible with the sufferer’s medical care so that you can ask questions of doctors and other healthcare professionals.
  • Don’t hesitate to ask for help from other family members or friends.
  • Take advantage of support services in your community, such as respite care, if they’re available.
  • Don’t feel guilty if you feel frustrated or angry with the sufferer.
  • Take time to yourself whenever possible, and don’t neglect your own emotional and physical needs.
  • Find a support group for caregivers.

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

Dementia Brain Science

Research into the causes and progression of dementia is focused on finding new ways to diagnose and treat the disorder, and there is hope that a more thorough understanding of the chemical mechanisms involved could lead to drugs that prevent dementia or reverse its effects. As research is ongoing, scientists are finding ways to build on what they already know about dementia, and they are also regularly making new discoveries. For example:

  • Researchers are working to develop new drugs that don’t just treat the symptoms of dementia, but that could disrupt the chemical processes in the brain that cause dementia in the first place. Scientists have a fairly complete understanding of how protein clumping causes neurological damage in Alzheimer’s patients, for example, and they are attempting to find drugs that halt the process that creates the clumps.
  • Scientists are discovering new forms of dementia that seem to arise from different brain-chemistry problems than those that cause previously known forms of dementia. An example is limbic-predominant age-related TDP-43 encephalopathy (LATE) a recently identified type of dementia that looks like Alzheimer’s but that seems to be caused by an entirely different brain protein.

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

Dementia Research

Scientists are working on several research projects to expand on what is known about Dementia.  The research will improve knowledge about the factors that increase the risk for Dementia, as well as the causes, and best treatments, and will aid people living with Dementia and their caregivers. We are currently gathering the information required to support projects such as Low-Dose Lithium for the Treatment of Behavioral Symptoms in Frontotemporal Dementia and Improving Well-Being for Older Adult Family Dementia Caregivers

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

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