Project Description

Autism Fast Facts

Autism is a brain-based developmental disorder. Autism spectrum disorders (ASD) are exploding in incidence in the United States. No one knows whether the increase reflects rising numbers or new awareness.

Today, the umbrella term of ASD includes autism, Asperger’s Syndrome, Pervasive Developmental Disorder-Not Otherwise Specified (PDD-NOS), and Childhood Disintegrative Disorder (regressive autism).

Autistic children inhabit a solitary internal world. People with ASD have difficulty communicating and interacting with others.

Most children were still being diagnosed after age 4, though autism can be reliably diagnosed as early as age 2. 

What is Autism Spectrum Disorder?

Autism is a brain-based developmental disorder. People with ASD have difficulty communicating and interacting with others. Children diagnosed with ASD typically are unresponsive to social cues, appear remote or preoccupied, and have difficulty expressing abstract feelings. Autistic children often seem oblivious to other people’s emotions.

Individuals with autism typically don’t initiate or sustain conversations except on topics of interest to them. Up to a third of children with autism don’t speak at all. Nearly a third have an intellectual disability. However, significant language delays are rare in people with a high-functioning form of ASD.

Autism was classified as a disorder in 1943 by Dr. Leo Kanner, a psychiatrist at Johns Hopkins University School of Medicine. Today, the umbrella term of ASD includes autism, the disorder formerly known as Asperger’s syndrome, Pervasive Developmental Disorder-Not Otherwise Specified (PDD-NOS), and Childhood Disintegrative Disorder (regressive autism).

The high-functioning form of the disorder, formerly known as “Asperger’s syndrome,” is now classified as an autism spectrum disorder. Pervasive Developmental Disorder (PDD) is a brain-based developmental disorder that interferes with the perception of social cues and sensory information. Children with the disorder suffer from the bewildering sensory overload that impairs brain function.

In recent years, the rate of diagnosis of autism spectrum disorders (ASD) has increased significantly in the United States. It’s not clear whether the rise in diagnosed cases of ASD stems from an actual increase in the prevalence of the disorders or from increased awareness of their symptoms.

Symptoms and Effects of ASD

Autism is a spectrum disorder, meaning that not everyone experiences it in the same way. There is wide variability in the symptoms and behaviors of people with a disorder on the autism spectrum.

Symptoms of ASD can include:

  • Problems with verbal and nonverbal communication, including spoken language, gestures, facial expressions, tone of voice, and eye contact
  • Expressing and recognizing emotions in self and others
  • Anxiety in social situations
  • Sensitivity to sensory overstimulation
  • Repetitive or ritualistic behaviors
  • Intense interest in narrow subjects
  • Need for routines or rules to follow

Other characteristics of ASD may include:

  • Autism is associated with repetitive patterns of behavior, such as arm flapping and rocking from side to side. Difficulties appear early in development, generally by age three.
  • Up to 40% of people with autism also suffer from anxiety.
  • People with autism often struggle to understand social nuances.
  • People with autism often suffer from gastrointestinal (GI) problems, seizures, sleep disturbances, attention-deficit/hyperactivity disorder (ADHD), and phobias.
  • Despite these challenges, some individuals with ASD show unique strengths in problem-solving and attention to detail.
  • Children with the high-functioning form of ASD sometimes display extraordinary abilities with memory, music, or mathematics.

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

What Causes Autism Spectrum Disorder?

The causes of autism have not yet been discovered. Some studies have identified risk factors that seem to be associated with ASD, but much of the research into causes has been inconclusive. The following factors may increase the risk of autism, but none of them is, by any means, a reliable predictor of the disorder:

  • Male gender. Boys are four times more likely than girls to develop ASD.
  • A mother or father who is 35 or older at the time of conception.
  • Pregnancy and birth complications, including extreme prematurity (earlier than 26 weeks), low birth weight, and multiple births (twins, triplets, etc.).
  • Pregnancies spaced less than one year apart.
  • Chronic stress during pregnancy.
  • Vitamin D deficiency during pregnancy.
  • Too much or too little folic acid (also called folate or vitamin B). Pregnant women should talk to their doctor before taking vitamin supplements.
  • Viral infections during pregnancy. Exposure of the mother to rubella (German measles) or a cytomegalovirus (CMV) infection during pregnancy may increase the risk.
  • Use of certain drugs, such as valproic acid, thalidomide, and misoprostol, during pregnancy.
  • Environmental triggers and exposure to toxic chemicals such as bisphenol-A (BPA).

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

Is Autism Spectrum Disorder Hereditary?

Autism arises from a complex interplay of genes and the environment. Genetics plays a role in ASD, but scientists still don’t know exactly how risk for the disorder is inherited. While some genes and gene variations are known to raise susceptibility to the disorder, the presence of the genes doesn’t necessarily mean that an individual will develop ASD. Even when one identical twin has autism, the other twin has only a 60 percent chance of receiving the same diagnosis.

Although environmental factors are almost certainly partly to blame for the development of autism, a recent study has suggested that as much as 80% of the risk for the disorder comes from genetics.

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

How is Autism Spectrum Disorder Detected?

There are currently no tests to predict autism. Genetic testing is available for people with a strong family history of ASD. Genetic counselors can help people make decisions about the need for testing.

ASD usually appears early in life, causing delays in learning to talk, play, and interact. Yet some children are misdiagnosed or are not diagnosed until later in life.

Generally, the earlier a child is diagnosed, the better. Some people with ASD learn to communicate by pointing to pictures or use a computer tablet with special language applications. Parents magazine publishes a list of apps that help kids with ASD learn the alphabet, math skills, and vocabulary.

Speech-language therapy can also help autistic children learn to express feelings and emotions. Many people with ASD have trouble reading facial expressions. They also find it difficult to understand the nonverbal aspects of language, such as social cues and body language.

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

How is Autism Spectrum Disorder Diagnosed?

No lab test, blood work, or imaging exams are used to diagnose ASD. Pediatricians normally do an assessment at a child’s 18- and 24-month checkups to look for developmental signs of the disorder.

Doctors observe the child’s behavior and talk to parents. If concerns arise, an autism specialist may be recommended to evaluate a child’s behavior and development to make a diagnosis.

If ASD is suspected, healthcare professionals will work through a checklist of questions in pursuit of a diagnosis. Some of these questions might include:

  • Are the child’s behaviors odd or repetitive?
  • Does the child have trouble making eye contact?
  • Does the child interact with other people?
  • Does the child respond to someone’s voice?
  • Is the child sensitive to light, noise, or temperature?
  • Does the child have sleep or digestive problems?
  • Does the child seem irritable or angry?

PLEASE CONSULT A PHYSICIAN FOR MORE INFORMATION.

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

How is Autism Spectrum Disorder Treated?

Current approaches to the treatment of ASD focus on managing behavioral symptoms and helping with social skills. The most successful Interventions are in the areas of occupational therapy, speech, and language therapy.

So far, no drugs have been approved by the FDA to address the core symptoms of ASD. Risperidone and Aripiprazole may be used to treat irritability associated with ASD. Some other medications, such as selective serotonin reuptake inhibitors (SSRIs), are sometimes used in an “off-label” way (meaning to treat symptoms other than the ones for which the drugs are approved) to treat symptoms of ASD.

A wide range of behavioral therapies and psychotherapy approaches have proven to be effective at treating ASD. Commonly used therapies include:

  • Behavioral management therapy
  • Cognitive behavior therapy (CBT)
  • Educational and school-based therapies
  • Joint attention therapy
  • Nutritional therapy
  • Occupational therapy
  • Parent-mediated therapy
  • Physical therapy
  • Social skills training
  • Speech-language therapy

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

How Does Autism Spectrum Disorder Progress?

The social, developmental, behavioral, and emotional symptoms of ASD can lead, over time, to a long list of physical, mental and social health problems. Some mental health issues often co-occur with ASD, and some physical complications can arise from long-term behavioral aspects of ASD.

Long-term complications can include:

  • Social isolation
  • School or work difficulties
  • Financial problems
  • Inability to live independently
  • Depression or anxiety
  • Obsessive-compulsive disorder
  • Eating disorders
  • Gastrointestinal problems
  • Muscular or skeletal problems (from unusual posture, gait, or repetitive movements)
  • Epilepsy
  • Dental problems (from lack of hygiene, jaw clenching, or teeth grinding)
  • Allergies or skin problems
  • Injuries (or death) caused by lack of awareness of safety concerns

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

How is Autism Spectrum Disorder Prevented?

There is no known way to prevent autism or to cure it when it occurs. The causes of the disorder are unknown, and avoiding speculative risk factors has not proven to be effective at reducing the occurrence of ASD.

The best course of action is early detection and prompt treatment of autism when it is diagnosed. The earlier that a child is diagnosed with the disorder, the better the chance that therapeutic intervention will help to control symptoms and minimize their impact down the road.

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

Autism Spectrum Disorder Caregiver Tips

Some of the ways you can help your child cope with autism include:

  • Educate yourself. The more you know, the better you’ll be able to help your child. That means you should learn as much as you can about autism, but it also means you should know about your child’s individual experience with the disorder. Each child is different, with different sensitivities, triggers, challenges, and strengths. You can best support your child when you’re an expert on his or her autism.
  • Know the difference between science and pseudo-science. Misinformation surrounding autism abounds, and you need to know how to recognize it. Rely on authoritative sources, and don’t be swayed by people who offer dubious causes or miraculous cures for the disorder.
  • Provide a safe, comforting environment. Make sure your child has a space that’s free of the things that make him or her uncomfortable.
  • Provide consistency. Stick to routines, schedules, rules, and reliable ways of doing things.
  • Be an advocate for your child. Only you know what’s best for your child, and it’s up to you to be sure that caregivers, teachers, family members, and everyone else knows how to best support your family.

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

Autism Spectrum Disorder Brain Science

Research is ongoing in many different directions to increase our knowledge of autism, its causes, its identification, and its effective treatment. Current areas of research include:

  • Researchers are looking at the relationship between autism and related disorders such as tuberous sclerosis complex, Fragile X Syndrome, Phelan-McDermid syndrome, and Rett Syndrome. The hope is that learning about these disorders can help scientists to understand how autism develops and to predict when it may occur.
  • Studies of the development of nerve cells in the brain are aimed at discovering how abnormal communication between these cells may cause autism.
  • Imaging studies are looking for differences in brain activity between people with autism and people without the disorder. An understanding of these differences could lead to therapies or medications that could improve symptoms of ASD.

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

Autism Spectrum Disorder Research

Scientists are working on several research projects to expand on what is known about Autism. The research will improve knowledge about the factors that increase the risk for Autism, as well as the causes, and best treatments, and will aid people living with Autism and their caregivers.

We are currently gathering the information required to support projects such as Study of Neuroimaging Biomarkers of Social Cognition Deficits in Adolescents (Age 13-17) With Autism Spectrum Disorder and Effects of GabapentinBrain Mechanisms for Language Processing in Adolescents With Autism Spectrum Disorder (BSL), and Pivotal Response Treatment for Children With Autism Spectrum Disorders (PRT)

*The medical information we gather and publish is vetted and intended to be up to date, accurate and express a spectrum of recognized scientific and medical points of view. The information comes from a nucleus of informed scientists, medical doctors, peer-reviewed scientific journals and the National Institute of Health. Please note, differing points of view among scientists and physicians are common. Every effort is employed to ensure the accuracy of these different points of view. That notwithstanding, it is incumbent on persons using this information to consult with his/her physician before reaching any conclusions. Our medical information and publications are not intended to be a substitute for consultation with one’s physician.

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